Gelatinase activity ofNeisseria gonorrhoeae
نویسندگان
چکیده
منابع مشابه
Gelatinase Activity by Marine Fungi.
Gelatinase activity was detectable in the culture filtrates of 13 of 14 species of marine fungi tested. The fungi were grown under conditions of submerged culture in a medium consisting of corn meal, soybean meal, and CaCO(3). The degree of enzymatic activity did not necessarily correlate with the amino nitrogen content of the filtrates. Eight of the filtrates contained measurable quantities of...
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Matrix metalloproteinases (MMPs), and in particular gelatinases (MMP-2 and MMP-9), play a key role in cancer progression. However, clinical trials in which MMP inhibitors were tested in cancer patients have been disappointing. Whereas many reasons have been postulated to explain the failure of the clinical trials, lack of inhibitor selectivity was a major limitation. Thus, despite the consensus...
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OBJECTIVES Gelatinases (MMP2 and MMP9) are expressed in giant-cell arteritis (GCA) and are thought to play a role in vessel disruption. However, their activation status and enzymatic activity have not been evaluated. Our aim was to investigate the distribution and proteolytic activity of gelatinases in GCA lesions at different stages. METHODS Expression of MMP2, MMP9, MMP2-activator MMP14 and...
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From the *Hautklinik, Ruprecht Karls University, Heidelberg, Federal Republic of Germany, the tNeisseria Reference Laboratory, Harborview Medical Center, Seattle, Washington, United States ofAmerica, the Klinikfur Dermatologie und Venerologie, University Medical School, Lubeck, Federal Republic of Germany, the §Genetic Systems Corporation, Seattle, and the UDepartment ofMedicine, University of ...
متن کاملActivity of eight antimicrobial agents in vitro against N. Gonorrhoeae.
The sensitivity of four groups of gonococcal strains to ampicillin (Am), penicillin (P), tetracycline (T), rifampicin (Ri), spectinomycin (Sp), sulphamethoxazole (Su), trimethoprim (Tr), and a combination of Su and Tr in the ratio 5:1 (Su/Tr 5:1) has been determined. The various groups of strains were isolated from male civilians (MC), female civilians (FC), and sailors (S) in Rotterdam (R) in ...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1977
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.1977.tb00904.x